Homo sapiens Protein: GZMK
Summary
InnateDB Protein IDBP-20771.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GZMK
Protein Name granzyme K (granzyme 3; tryptase II)
Synonyms TRYP2;
Species Homo sapiens
Ensembl Protein ENSP00000231009
InnateDB Gene IDBG-20767 (GZMK)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Secreted. Cytoplasmic granule.
Disease Associations
Tissue Specificity Expressed in lung, spleen, thymus and peripheral blood leukocytes.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
Experimentally validated
Total 18 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain
IPR015420 Peptidase S1A, nudel
PFAM PF00089
PF09342
PRINTS PR00722
PIRSF
SMART SM00020
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P49863
PhosphoSite PhosphoSite-P49863
TrEMBL
UniProt Splice Variant
Entrez Gene 3003
UniGene
RefSeq NP_002095
HUGO HGNC:4711
OMIM 600784
CCDS CCDS3964
HPRD 02872
IMGT
EMBL AK312074 BC035802 CH471123 U26174 U35237
GenPept AAA74578 AAA79063 AAH35802 BAG35010 EAW54899