Version 5.4
Mus musculus Protein: Esf1
Summary
InnateDB Protein IDBP-208065.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Esf1
Protein Name ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
Synonyms 2610101J03Rik; ABTAP; AW545818; C79684;
Species Mus musculus
Ensembl Protein ENSMUSP00000036523
InnateDB Gene IDBG-208063 (Esf1)
Protein Structure
UniProt Annotation
Function May constitute a novel regulatory system for basal transcription. Negatively regulates ABT1 (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus, nucleolus {ECO:0000250}. Nucleus, nucleoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0008150 biological_process
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
Protein Structure and Domains
PDB ID MGI:1913830
InterPro IPR012580 NUC153
PFAM PF08159
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3V1V3
PhosphoSite PhosphoSite-Q3V1V3
TrEMBL Q8K089
UniProt Splice Variant
Entrez Gene 66580
UniGene Mm.401402
RefSeq NP_001074559
MGI ID
MGI Symbol Esf1
OMIM
CCDS CCDS38250
HPRD
IMGT
EMBL AK040644 AK132230 BC032932 BC150893
GenPept AAH32932 AAI50894 BAC30655 BAE21046

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca