Version 5.4
Homo sapiens Protein: RFX2
Summary
InnateDB Protein IDBP-21099.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RFX2
Protein Name regulatory factor X, 2 (influences HLA class II expression)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000352076
InnateDB Gene IDBG-21095 (RFX2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 3 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR003150 DNA-binding RFX-type winged-helix domain
IPR007668 RFX1 transcription activation region
PFAM PF02257
PF04589
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P48378
PhosphoSite PhosphoSite-P48378
TrEMBL Q75MR3
UniProt Splice Variant
Entrez Gene 5990
UniGene Hs.677653
RefSeq
HUGO HGNC:9983
OMIM 142765
CCDS CCDS12157
HPRD 00824
IMGT
EMBL AC005784 AC011444 AC011471 AC104538 AK024288 AK291196 BC028579 BC071571 X76091
GenPept AAC62839 AAH28579 AAH71571 BAF83885 BAG51286 CAA53705

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca