InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Echs1

Summary

InnateDB Protein

IDBP-211667.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Echs1

Protein Name

enoyl Coenzyme A hydratase, short chain, 1, mitochondrial

Synonyms

C80529;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000026538

InnateDB Gene

IDBG-211665 (Echs1)

Protein Structure

UniProt Annotation

Function

Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate. {ECO:0000250}.

Subcellular Localization

Mitochondrion matrix {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.

Experimentally validated
Total	11 [view]
Protein-Protein	11 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	31 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004300	enoyl-CoA hydratase activity
GO:0005515	protein binding

Biological Process

GO:0006635	fatty acid beta-oxidation
GO:0008152	metabolic process

Cellular Component

GO:0005739	mitochondrion
GO:0005759	mitochondrial matrix
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:2136460

InterPro

IPR001753 Crotonase superfamily
IPR029045 ClpP/crotonase-like domain

PFAM

PF00378

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8BH95

PhosphoSite

PhosphoSite-Q8BH95

TrEMBL

UniProt Splice Variant

Entrez Gene

93747

UniGene

Mm.408900

RefSeq

NP_444349

MGI ID

MGI Symbol

Echs1

OMIM

CCDS

CCDS21964

HPRD

IMGT

EMBL

AK040391 AK044954 AK088018 AK167404 BC002178 BC057971 BC072658

GenPept

AAH02178 AAH57971 AAH72658 BAC30583 BAC32157 BAC40099 BAE39493