Version 5.4
Homo sapiens Protein: YTHDC1
Summary
InnateDB Protein IDBP-21316.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol YTHDC1
Protein Name YTH domain containing 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000347888
InnateDB Gene IDBG-21314 (YTHDC1)
Protein Structure
UniProt Annotation
Function RNA-binding protein that regulates alternative splice site selection. {ECO:0000269PubMed:20167602}.
Subcellular Localization Nucleus {ECO:0000269PubMed:20167602}. Note=Localizes to a novel subnuclear structure, the YT bodies.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 44 experimentally validated interaction(s) in this database.
Experimentally validated
Total 44 [view]
Protein-Protein 44 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006376 mRNA splice site selection
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR007275 YTH domain
PFAM PF04146
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96MU7
PhosphoSite PhosphoSite-Q96MU7
TrEMBL J3KS01
UniProt Splice Variant
Entrez Gene 91746
UniGene Hs.605625
RefSeq NP_588611
HUGO HGNC:30626
OMIM
CCDS CCDS3522
HPRD 11689
IMGT
EMBL AB075846 AC074378 AK056430 BC041119 BC053863
GenPept AAH41119 AAH53863 AAY41024 BAB71181 BAB85552

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca