InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NCAM2

Summary

InnateDB Protein

IDBP-227960.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NCAM2

Protein Name

neural cell adhesion molecule 2

Synonyms

NCAM21;

Species

Homo sapiens

Ensembl Protein

ENSP00000383392

InnateDB Gene

IDBG-1027 (NCAM2)

Protein Structure

UniProt Annotation

Function

May play important roles in selective fasciculation and zone-to-zone projection of the primary olfactory axons.

Subcellular Localization

Cell membrane; Single-pass type I membrane protein.

Disease Associations

Tissue Specificity

Expressed most strongly in adult and fetal brain.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	2 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0007158	neuron cell-cell adhesion
GO:0007413	axonal fasciculation
GO:0007608	sensory perception of smell

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane
GO:0030424	axon

Protein Structure and Domains

PDB ID

InterPro

IPR003596 Immunoglobulin V-set, subgroup
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR003961 Fibronectin, type III
IPR007110 Immunoglobulin-like domain
IPR009138 Neural cell adhesion
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin

PFAM

PF00041
PF01108
PF07679
PF07686
PF00047

PRINTS

PR01838

PIRSF

SMART

SM00406
SM00408
SM00409
SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt