InnateDB Protein
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IDBP-228598.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SFI1
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Protein Name
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Sfi1 homolog, spindle assembly associated (yeast)
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Synonyms
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hSfi1p; PISD; PPP1R139;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000383146
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InnateDB Gene
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IDBG-4730 (SFI1)
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Protein Structure
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Function |
Plays a role in the dynamic structure of centrosome- associated contractile fibers via its interaction with CETN2. {ECO:0000269PubMed:16956364}.
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Subcellular Localization |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269PubMed:14504268, ECO:0000269PubMed:16956364}. Note=Localized close to the centriole.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
9
[view]
|
Protein-Protein |
9
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
|
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Predicted by orthology |
Total |
1 [view]
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|
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR013763
Cyclin-like
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
SM00385
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TIGRFAMs |
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Modification |
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SwissProt |
A8K8P3
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PhosphoSite |
PhosphoSite-A8K8P3
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
9814
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UniGene |
Hs.679749
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RefSeq |
NP_001245256
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HUGO |
HGNC:29064
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OMIM |
612765
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CCDS |
CCDS58804
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HPRD |
11550
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IMGT |
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EMBL |
AB011114
AK292408
AK293987
AK303362
AL096701
AL096768
AL109802
BC021576
BC110814
BC129926
BC129945
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GenPept |
AAH21576
AAI10815
AAI29927
AAI29946
BAA25468
BAF85097
BAH11642
BAH13949
CAH70755
CAI12881
CAI23034
CAM13202
CAM14700
CAM14701
CAM28334
CAX14857
CAX14858
CAX15240
CAX15241
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