InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PPCDC

Summary

InnateDB Protein

IDBP-23009.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PPCDC

Protein Name

phosphopantothenoylcysteine decarboxylase

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000343190

InnateDB Gene

IDBG-23007 (PPCDC)

Protein Structure

UniProt Annotation

Function

Necessary for the biosynthesis of coenzyme A. Catalyzes the decarboxylation of 4-phosphopantothenoylcysteine to form 4'- phosphopantotheine. {ECO:0000269PubMed:11923312, ECO:0000269PubMed:15581364}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004633	phosphopantothenoylcysteine decarboxylase activity

Biological Process

GO:0006766	vitamin metabolic process
GO:0006767	water-soluble vitamin metabolic process
GO:0008152	metabolic process
GO:0009108	coenzyme biosynthetic process
GO:0015937	coenzyme A biosynthetic process
GO:0015939	pantothenate metabolic process
GO:0044281	small molecule metabolic process