InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DOPEY2

Summary

InnateDB Protein

IDBP-231281.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DOPEY2

Protein Name

dopey family member 2

Synonyms

21orf5; C21orf5;

Species

Homo sapiens

Ensembl Protein

ENSP00000382104

InnateDB Gene

IDBG-2942 (DOPEY2)

Protein Structure

UniProt Annotation

Function

May be involved in protein traffic between late Golgi and early endosomes. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Ubiquitously expressed. Overexpressed in lymphoblasts from Down syndrome patients. {ECO:0000269PubMed:10950924, ECO:0000269PubMed:12767918}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0006895	Golgi to endosome transport
GO:0007029	endoplasmic reticulum organization
GO:0007275	multicellular organismal development
GO:0015031	protein transport
GO:0050890	cognition

Cellular Component

GO:0000139	Golgi membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR007249 Dopey, N-terminal

PFAM

PF04118

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9Y3R5

PhosphoSite

PhosphoSite-Q9Y3R5

TrEMBL

F8W8U9

UniProt Splice Variant

Entrez Gene

9980

UniGene

Hs.204575

RefSeq

NP_005119

HUGO

HGNC:1291

OMIM

604803

CCDS

CCDS13643

HPRD

07271

IMGT

EMBL

AB023150 AJ237839 AP000689 AP000690 AP000691 AP000692 AP001725 BC012791 CH471079

GenPept

AAH12791 BAA76777 BAA89431 BAA95548 CAB41415 EAX09743 EAX09744