InnateDB Protein
|
IDBP-233532.7
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
TGOLN2
|
Protein Name
|
trans-golgi network protein 2
|
Synonyms
|
TGN38; TGN46; TGN48; TGN51; TTGN2;
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000381312
|
InnateDB Gene
|
IDBG-58918 (TGOLN2)
|
Protein Structure
|
|
Function |
May be involved in regulating membrane traffic to and from trans-Golgi network.
|
Subcellular Localization |
Cell membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single- pass type I membrane protein. Note=Primarily in trans-Golgi network. Cycles between the trans-Golgi network and the cell surface returning via endosomes.
|
Disease Associations |
|
Tissue Specificity |
Isoform TGN46 is widely expressed. Isoform TGN51 is more abundant in fetal lung and kidney. Isoform TGN48 is barely expressed in embryonic kidney and promyelocytic cells.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
17
[view]
|
Protein-Protein |
16
[view]
|
Protein-DNA |
1
[view]
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
|
PFAM |
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
O43493
|
PhosphoSite |
PhosphoSite-O43493
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
10618
|
UniGene |
Hs.738852
|
RefSeq |
NP_001193773
|
HUGO |
HGNC:15450
|
OMIM |
603062
|
CCDS |
CCDS56127
|
HPRD |
04343
|
IMGT |
|
EMBL |
AC093162
AF027515
AF027516
AF029313
AF029314
AF029315
AF029316
AK126465
AK222829
AK223063
AK312479
BC008461
BC028219
BX640868
CH471053
U62390
X94333
|
GenPept |
AAB96906
AAB96907
AAB96908
AAC39539
AAC39541
AAC39542
AAH08461
AAH28219
AAY24095
BAC86559
BAD96549
BAD96783
BAG35383
CAA64002
CAE45926
EAW99535
EAW99536
EAW99539
|
|
|