Version 5.4
Homo sapiens Protein: DUSP15
Summary
InnateDB Protein IDBP-233894.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DUSP15
Protein Name dual specificity phosphatase 15
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000381158
InnateDB Gene IDBG-64150 (DUSP15)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm {ECO:0000305PubMed:15138252}.Isoform 3: Cell membrane; Lipid-anchor; Cytoplasmic side.
Disease Associations
Tissue Specificity Highly expressed in testis. {ECO:0000269PubMed:15138252}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004725 protein tyrosine phosphatase activity
GO:0005515 protein binding
GO:0008138 protein tyrosine/serine/threonine phosphatase activity
Biological Process
GO:0006470 protein dephosphorylation
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0042127 regulation of cell proliferation
GO:0046330 positive regulation of JNK cascade
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR029021 Protein-tyrosine phosphatase-like
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H1R2
PhosphoSite PhosphoSite-Q9H1R2
TrEMBL
UniProt Splice Variant
Entrez Gene 128853
UniGene Hs.739467
RefSeq NP_817130
HUGO HGNC:16236
OMIM
CCDS CCDS42862
HPRD 13252
IMGT
EMBL AK091960 AK097430 AL160175 BC056911 BM554314 CH471077
GenPept AAH56911 BAC05048 BAG52450 CAI12819 CAI12821 CAI12822 EAW76410

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca