InnateDB Protein
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IDBP-235559.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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HAGH
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Protein Name
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hydroxyacylglutathione hydrolase
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Synonyms
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GLO2; GLX2; GLXII; HAGH1;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000380511
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InnateDB Gene
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IDBG-9334 (HAGH)
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Protein Structure
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Function |
Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid.
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Subcellular Localization |
Isoform 1: Mitochondrion matrix.Isoform 2: Cytoplasm.
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Disease Associations |
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Tissue Specificity |
Expressed in liver and kidney. {ECO:0000269PubMed:15117945}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
6
[view]
|
Protein-Protein |
6
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001279
Beta-lactamase-like
IPR017782
Hydroxyacylglutathione hydrolase
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PFAM |
PF00753
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PRINTS |
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PIRSF |
PIRSF005457
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SMART |
SM00849
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TIGRFAMs |
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Modification |
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SwissProt |
Q16775
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PhosphoSite |
PhosphoSite-Q16775
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TrEMBL |
H3BV79
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UniProt Splice Variant |
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Entrez Gene |
3029
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UniGene |
Hs.157394
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RefSeq |
NP_001035517
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HUGO |
HGNC:4805
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OMIM |
138760
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CCDS |
CCDS32366
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HPRD |
00731
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IMGT |
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EMBL |
AC012180
AE006639
AK290155
AK298174
AK299173
BC000840
BC002627
X90999
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GenPept |
AAH00840
AAH02627
AAK61294
BAF82844
BAG60445
BAG61219
CAA62483
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