Version 5.4
Homo sapiens Protein: MDP1
Summary
InnateDB Protein IDBP-236668.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MDP1
Protein Name magnesium-dependent phosphatase 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000380045
InnateDB Gene IDBG-236666 (MDP1)
Protein Structure
UniProt Annotation
Function Magnesium-dependent phosphatase which may act as a tyrosine phosphatase. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004725 protein tyrosine phosphatase activity
GO:0016791 phosphatase activity
GO:0046872 metal ion binding
Biological Process
GO:0035335 peptidyl-tyrosine dephosphorylation
Cellular Component
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR010033 HAD-superfamily phosphatase, subfamily IIIC
IPR010036 Magnesium-dependent phosphatase-1, eukaryotic/arcaheal type
IPR023214 HAD-like domain
PFAM PF12689
PF00702
PF08282
PF13419
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86V88
PhosphoSite PhosphoSite-Q86V88
TrEMBL
UniProt Splice Variant
Entrez Gene 145553
UniGene
RefSeq NP_001186750
HUGO HGNC:28781
OMIM
CCDS CCDS55908
HPRD 14695
IMGT
EMBL AK092821 BC046912 BC051382
GenPept AAH46912 AAH51382 BAC03984

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca