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InnateDB Protein
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IDBP-237719.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CDKN1B
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Protein Name
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cyclin-dependent kinase inhibitor 1B (p27, Kip1)
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Synonyms
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CDKN4; KIP1; MEN1B; MEN4; P27KIP1;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000379629
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InnateDB Gene
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IDBG-20317 (CDKN1B)
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Protein Structure
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| Function |
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| Subcellular Localization |
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 157 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
157
[view]
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| Protein-Protein |
145
[view]
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| Protein-DNA |
11
[view]
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| Protein-RNA |
0
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| DNA-DNA |
1
[view]
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| RNA-RNA |
0
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| DNA-RNA |
0
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| Predicted by orthology |
| Total |
24 [view]
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Molecular Function |
| Accession |
GO Term |
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GO:0004861
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cyclin-dependent protein serine/threonine kinase inhibitor activity
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| Biological Process |
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GO:0007050
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cell cycle arrest
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GO:0071901
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negative regulation of protein serine/threonine kinase activity
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| Cellular Component |
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| PDB ID |
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| InterPro |
IPR003175
Cyclin-dependent kinase inhibitor
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| PFAM |
PF02234
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| PRINTS |
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
E7ES52
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| UniProt Splice Variant |
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| Entrez Gene |
1027
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| UniGene |
Hs.628402
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| RefSeq |
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| HUGO |
HGNC:1785
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| OMIM |
600778
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| CCDS |
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| HPRD |
02867
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| IMGT |
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| EMBL |
AC008115
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| GenPept |
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Version 5.4