InnateDB Protein
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IDBP-239372.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SPECC1
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Protein Name
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sperm antigen with calponin homology and coiled-coil domains 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000378901
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InnateDB Gene
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IDBG-35228 (SPECC1)
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Protein Structure
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Function |
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Subcellular Localization |
Nucleus {ECO:0000269PubMed:15602574}.
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Disease Associations |
Note=A chromosomal aberration involving CYTSB may be a cause of juvenile myelomonocytic leukemia. Translocation t(5;17)(q33;p11.2) with PDGFRB.
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Tissue Specificity |
Highly expressed in testis. Barely detectable in other tissues. Also highly expressed in some cancer cell lines. {ECO:0000269PubMed:15602574}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
14
[view]
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Protein-Protein |
14
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001715
Calponin homology domain
IPR022613
Calmodulin-regulated spectrin-associated protein, CH domain
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PFAM |
PF00307
PF11971
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PRINTS |
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PIRSF |
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SMART |
SM00033
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TIGRFAMs |
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Modification |
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SwissProt |
Q5M775
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PhosphoSite |
PhosphoSite-Q5M775
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TrEMBL |
J3QQM0
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UniProt Splice Variant |
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Entrez Gene |
92521
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UniGene |
Hs.740153
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RefSeq |
NP_001028727
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HUGO |
HGNC:30615
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OMIM |
608793
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CCDS |
CCDS42281
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HPRD |
12301
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IMGT |
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EMBL |
AB041533
AC004702
AC005730
AC007963
AC008088
AK295093
AK298601
AY816326
AY816327
AY816328
AY816329
BC021123
BC033618
BC050058
BK005598
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GenPept |
AAH21123
AAH33618
AAH50058
AAW29999
AAW30000
AAW30001
AAW30002
BAB16440
BAG58132
BAG60786
DAA05629
DAA05630
DAA05631
DAA05632
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