InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: AMT

Summary

InnateDB Protein

IDBP-239769.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

AMT

Protein Name

aminomethyltransferase

Synonyms

GCE; GCST; GCVT; NKH;

Species

Homo sapiens

Ensembl Protein

ENSP00000378747

InnateDB Gene

IDBG-34823 (AMT)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	1 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004047	aminomethyltransferase activity
GO:0008483	transaminase activity

Biological Process

GO:0006546	glycine catabolic process
GO:0032259	methylation

Cellular Component

GO:0005739

mitochondrion

Protein Structure and Domains

PDB ID

InterPro

IPR006222 Glycine cleavage T-protein, N-terminal
IPR006223 Glycine cleavage system T protein
IPR013977 Glycine cleavage T-protein, C-terminal barrel domain
IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA
IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain

PFAM

PF01571
PF08669

PRINTS

PIRSF

PIRSF006487

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P48728