Version 5.4
Homo sapiens Protein: HLA-DMA
Summary
InnateDB Protein IDBP-239835.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HLA-DMA
Protein Name major histocompatibility complex, class II, DM alpha
Synonyms D6S222E; DMA; HLADM; RING6;
Species Homo sapiens
Ensembl Protein ENSP00000378714
InnateDB Gene IDBG-81652 (HLA-DMA)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0042613 MHC class II protein complex
Protein Structure and Domains
PDB ID
InterPro IPR001003 MHC class II, alpha chain, N-terminal
IPR003597 Immunoglobulin C1-set
IPR011162 MHC classes I/II-like antigen recognition protein
PFAM PF00993
PF07654
PRINTS
PIRSF
SMART SM00920
SM00407
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5SP00
UniProt Splice Variant
Entrez Gene 3108
UniGene Hs.717533
RefSeq
HUGO HGNC:4934
OMIM 142855
CCDS
HPRD 00830
IMGT
EMBL AL645941
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca