Homo sapiens Protein: KCNG3
Summary
InnateDB Protein IDBP-240505.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCNG3
Protein Name potassium voltage-gated channel, subfamily G, member 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000378424
InnateDB Gene IDBG-48503 (KCNG3)
Protein Structure
UniProt Annotation
Function Potassium channel subunit. Modulates channel activity.
Subcellular Localization Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Note=Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB1.
Disease Associations
Tissue Specificity Detected in many parts of the brain with the exception of the cerebellum, in testis, pancreas, lung, kidney, ovary, small intestine, colon, thymus, adrenal gland and spinal cord.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005251 delayed rectifier potassium channel activity
GO:0005515 protein binding
Biological Process
GO:0006811 ion transport
GO:0007268 synaptic transmission
GO:0034765 regulation of ion transmembrane transport
GO:0051260 protein homooligomerization
GO:0055085 transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0008076 voltage-gated potassium channel complex
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR000210 BTB/POZ-like
IPR003091 Potassium channel
IPR003131 Potassium channel tetramerisation-type BTB domain
IPR003968 Potassium channel, voltage dependent, Kv
IPR003969 Potassium channel, voltage dependent, Kv6
IPR003971 Potassium channel, voltage dependent, Kv9
IPR003974 Potassium channel, voltage dependent, Kv3
IPR005821 Ion transport domain
IPR011333 BTB/POZ fold
IPR013099 Two pore domain potassium channel domain
PFAM PF02214
PF00520
PF07885
PRINTS PR00169
PR01491
PR01492
PR01494
PR01498
PIRSF
SMART SM00225
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8TAE7
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 170850
UniGene Hs.352633
RefSeq NP_758847
HUGO HGNC:18306
OMIM 606767
CCDS CCDS42674
HPRD 16232
IMGT
EMBL AB070604 AC025750 AF348982 AF454547 AF454548 BC071558 CH471053
GenPept AAH71558 AAL83909 AAM93548 AAM93549 AAY24039 BAB85520 EAX00319