InnateDB Protein
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IDBP-240781.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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RAB3IL1
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Protein Name
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RAB3A interacting protein (rabin3)-like 1
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Synonyms
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GRAB;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000378313
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InnateDB Gene
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IDBG-50650 (RAB3IL1)
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Protein Structure
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Function |
Guanine nucleotide exchange factor (GEF) which may activate RAB3A, a GTPase that regulates synaptic vesicle exocytosis. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May also activate RAB8A and RAB8B. {ECO:0000269PubMed:20937701}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
6
[view]
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Protein-Protein |
6
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0005515
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protein binding
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GO:0017112
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Rab guanyl-nucleotide exchange factor activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR009449
GDPGTP exchange factor Sec2p
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PFAM |
PF06428
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8TBN0
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PhosphoSite |
PhosphoSite-Q8TBN0
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
5866
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UniGene |
Hs.13759
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RefSeq |
NP_037533
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HUGO |
HGNC:9780
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OMIM |
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CCDS |
CCDS8014
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HPRD |
10181
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IMGT |
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EMBL |
AF084557
BC022239
BC051820
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GenPept |
AAF28399
AAH22239
AAH51820
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