InnateDB Protein
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IDBP-242035.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ZFYVE1
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Protein Name
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zinc finger, FYVE domain containing 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000377757
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InnateDB Gene
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IDBG-11183 (ZFYVE1)
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Protein Structure
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Function |
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Subcellular Localization |
Golgi apparatus, Golgi stack. Endoplasmic reticulum. Note=Resides predominantly in the cisternal stacks of the Golgi. Colocalizes with TRIM13 on the perinuclear endoplasmic reticulum.
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Disease Associations |
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Tissue Specificity |
Isoform 1 is expressed in all tissues examined, including, brain, placenta, lung, liver, skeletal muscle, pancreas and kidney. Isoform 1 and isoform 2 are highly expressed in heart. Isoform 2 is also detected in the testis.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
7
[view]
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Protein-Protein |
7
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
GO:0010923
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negative regulation of phosphatase activity
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Cellular Component |
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PDB ID |
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InterPro |
IPR000306
FYVE zinc finger
IPR011011
Zinc finger, FYVE/PHD-type
IPR017455
Zinc finger, FYVE-related
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PFAM |
PF01363
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PRINTS |
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PIRSF |
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SMART |
SM00064
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TIGRFAMs |
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Modification |
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SwissProt |
Q9HBF4
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PhosphoSite |
PhosphoSite-Q9HBF4
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
53349
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UniGene |
Hs.335106
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RefSeq |
NP_848535
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HUGO |
HGNC:13180
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OMIM |
605471
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CCDS |
CCDS41969
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HPRD |
12017
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IMGT |
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EMBL |
AB046809
AF251025
AF311602
AF318319
AJ310569
AK027399
AL442663
BC053520
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GenPept |
AAG23748
AAH53520
AAK27339
AAL55826
BAB13415
BAB55085
CAC83950
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