Version 5.4
Homo sapiens Protein: TBC1D23
Summary
InnateDB Protein IDBP-242186.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TBC1D23
Protein Name TBC1 domain family, member 23
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000377700
InnateDB Gene IDBG-47238 (TBC1D23)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005097 Rab GTPase activator activity
Biological Process
GO:0032313 regulation of Rab GTPase activity
GO:0032680 regulation of tumor necrosis factor production
GO:0032755 positive regulation of interleukin-6 production
GO:0032851 positive regulation of Rab GTPase activity
GO:0050727 regulation of inflammatory response
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000195 Rab-GTPase-TBC domain
IPR001763 Rhodanese-like domain
PFAM PF00566
PF00581
PRINTS
PIRSF
SMART SM00164
SM00450
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NUY8
PhosphoSite PhosphoSite-Q9NUY8
TrEMBL B3KS68
UniProt Splice Variant
Entrez Gene 55773
UniGene Hs.605569
RefSeq NP_001186127
HUGO HGNC:25622
OMIM
CCDS CCDS56265
HPRD 07727
IMGT
EMBL AB449910 AC078783 AC093003 AK001750 AK001908 AK092926 AL713684 AY740521 BC010221 BC020955
GenPept AAH10221 AAH20955 AAW66944 BAA91881 BAA91973 BAG52630 BAH16653 CAD28488

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca