InnateDB Protein
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IDBP-242884.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SLC35B2
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Protein Name
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solute carrier family 35, member B2
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000377399
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InnateDB Gene
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IDBG-89538 (SLC35B2)
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Protein Structure
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Function |
Mediates the transport of adenosine 3'-phospho 5'- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. May indirectly participate in activation of the NF- kappa-B and MAPK pathways. {ECO:0000269PubMed:12716889}.
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Subcellular Localization |
Golgi apparatus membrane {ECO:0000269PubMed:12716889}; Multi-pass membrane protein {ECO:0000269PubMed:12716889}.
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Disease Associations |
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Tissue Specificity |
Highly expressed in the placenta, pancreas, mammary gland and skeletal muscle. Weakly or not expressed in colon, heart and prostate. {ECO:0000269PubMed:12716889}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
2
[view]
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Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
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PhosphoSite |
PhosphoSite-Q8TB61
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
347734
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UniGene |
Hs.661026
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RefSeq |
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HUGO |
HGNC:16872
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OMIM |
610788
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CCDS |
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HPRD |
11576
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IMGT |
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EMBL |
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GenPept |
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