Version 5.4
Homo sapiens Protein: ERGIC1
Summary
InnateDB Protein IDBP-242916.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ERGIC1
Protein Name endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000377374
InnateDB Gene IDBG-57829 (ERGIC1)
Protein Structure
UniProt Annotation
Function Possible role in transport between endoplasmic reticulum and Golgi. {ECO:0000303PubMed:15308636}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000269PubMed:15308636}; Multi-pass membrane protein {ECO:0000269PubMed:15308636}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000269PubMed:15308636}; Multi-pass membrane protein {ECO:0000269PubMed:15308636}. Golgi apparatus membrane {ECO:0000269PubMed:15308636}; Multi-pass membrane protein {ECO:0000269PubMed:15308636}. Note=Cycles between the endoplasmic reticulum and the Golgi.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
Experimentally validated
Total 20 [view]
Protein-Protein 20 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006888 ER to Golgi vesicle-mediated transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005789 endoplasmic reticulum membrane
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
Protein Structure and Domains
PDB ID
InterPro IPR012936 Endoplasmic reticulum vesicle transporter, C-terminal
PFAM PF07970
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q969X5
PhosphoSite PhosphoSite-Q969X5
TrEMBL
UniProt Splice Variant
Entrez Gene 57222
UniGene Hs.604241
RefSeq NP_001026881
HUGO HGNC:29205
OMIM
CCDS CCDS34292
HPRD 13836
IMGT
EMBL AB033007 AF267855 AL136753 BC012766 BC014490 CR533474
GenPept AAG44724 AAH12766 AAH14490 BAA86495 CAB66687 CAG38505

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca