InnateDB Protein
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IDBP-244312.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SERPINA10
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Protein Name
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serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000376809
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InnateDB Gene
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IDBG-18111 (SERPINA10)
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Protein Structure
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Function |
Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. Also inhibits factor XIa in the absence of cofactors. {ECO:0000269PubMed:11049983}.
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Subcellular Localization |
Secreted.
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Disease Associations |
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Tissue Specificity |
Expressed by the liver and secreted in plasma.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
4
[view]
|
Protein-Protein |
2
[view]
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Protein-DNA |
2
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0004867
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serine-type endopeptidase inhibitor activity
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GO:0008201
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heparin binding
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR023796
Serpin domain
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PFAM |
PF00079
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PRINTS |
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PIRSF |
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SMART |
SM00093
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TIGRFAMs |
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Modification |
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SwissProt |
Q9UK55
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PhosphoSite |
PhosphoSite-Q9UK55
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TrEMBL |
A0A024R6I6
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UniProt Splice Variant |
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Entrez Gene |
51156
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UniGene |
Hs.118620
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RefSeq |
NP_057270
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HUGO |
HGNC:15996
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OMIM |
605271
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CCDS |
CCDS9923
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HPRD |
09245
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IMGT |
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EMBL |
AF181467
AY358597
BC022261
BX248011
CH471061
EF621762
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GenPept |
AAD53962
AAH22261
AAQ88960
ABR09269
CAD62339
EAW81565
EAW81566
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