InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CIT

Summary

InnateDB Protein

IDBP-245487.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CIT

Protein Name

citron (rho-interacting, serine/threonine kinase 21)

Synonyms

CRIK; STK21;

Species

Homo sapiens

Ensembl Protein

ENSP00000376305

InnateDB Gene

IDBG-60008 (CIT)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	15 [view]
Protein-Protein	15 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004674	protein serine/threonine kinase activity
GO:0005083	small GTPase regulator activity
GO:0005524	ATP binding

Biological Process

GO:0006468	protein phosphorylation
GO:0007165	signal transduction
GO:0035556	intracellular signal transduction

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000961 AGC-kinase, C-terminal
IPR001180 Citron-like
IPR001849 Pleckstrin homology domain
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
IPR011072 HR1 rho-binding repeat
IPR017892 Protein kinase, C-terminal

PFAM

PF00780
PF00169
PF00130
PF02185
PF00433

PRINTS

PIRSF

SMART

SM00133
SM00036
SM00233
SM00109
SM00742

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite