InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PDCD2

Summary

InnateDB Protein

IDBP-246368.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PDCD2

Protein Name

programmed cell death 2

Synonyms

RP8; ZMYND7;

Species

Homo sapiens

Ensembl Protein

ENSP00000375940

InnateDB Gene

IDBG-99325 (PDCD2)

Protein Structure

UniProt Annotation

Function

May be a DNA-binding protein with a regulatory function. May play an important role in cell death and/or in regulation of cell proliferation.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Ubiquitous.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0019899	enzyme binding
GO:0046872	metal ion binding

Biological Process

GO:0006915

apoptotic process

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR002893 Zinc finger, MYND-type
IPR007320 Programmed cell death protein 2, C-terminal

PFAM

PF01753
PF04194

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q16342

PhosphoSite

PhosphoSite-Q16342

TrEMBL

F5H739

UniProt Splice Variant

Entrez Gene

5134

UniGene

Hs.743857

RefSeq

NP_001186391

HUGO

HGNC:8762

OMIM

600866

CCDS

CCDS56461

HPRD

02922

IMGT

EMBL

AK297343 AL031259 AY948416 AY948417 BC008378 S78085

GenPept

AAB34865 AAH08378 AAX51225 AAX51226 BAG59795 CAA20285