InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CRABP1

Summary

InnateDB Protein

IDBP-24655.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CRABP1

Protein Name

cellular retinoic acid binding protein 1

Synonyms

CRABP; CRABP-I; CRABPI; RBP5;

Species

Homo sapiens

Ensembl Protein

ENSP00000299529

InnateDB Gene

IDBG-24653 (CRABP1)

Protein Structure

UniProt Annotation

Function

Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors.

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:11909957}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001972	retinoic acid binding
GO:0005215	transporter activity
GO:0005501	retinoid binding
GO:0005515	protein binding
GO:0016918	retinal binding
GO:0019841	retinol binding

Biological Process

GO:0006810	transport
GO:0007165	signal transduction
GO:0007275	multicellular organismal development

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol

Protein Structure and Domains

PDB ID

InterPro

IPR000463 Cytosolic fatty-acid binding
IPR000566 Lipocalin/cytosolic fatty-acid binding domain
IPR011038 Calycin-like

PFAM

PF00061
PF08212

PRINTS

PR00178

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P29762

PhosphoSite

PhosphoSite-P29762

TrEMBL

F1T0F7

UniProt Splice Variant

Entrez Gene

1381

UniGene

RefSeq

NP_004369

HUGO

HGNC:2338

OMIM

180230

CCDS

CCDS10301

HPRD

07520

IMGT

EMBL

AB593091 BC022069 CH471136 CR457017 S74445

GenPept

AAB20773 AAH22069 BAJ84031 CAG33298 EAW99172