InnateDB Protein
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IDBP-246568.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TRAF3IP1
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Protein Name
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TNF receptor-associated factor 3 interacting protein 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000375851
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InnateDB Gene
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IDBG-84548 (TRAF3IP1)
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Protein Structure
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Function |
Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. {ECO:0000269PubMed:10791955, ECO:0000269PubMed:12812986, ECO:0000269PubMed:12935900}.
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Subcellular Localization |
Cytoplasm, cytoskeleton {ECO:0000269PubMed:12935900}. Cell projection, cilium {ECO:0000250}. Note=Microtubules.
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Disease Associations |
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Tissue Specificity |
Ubiquitous. {ECO:0000269PubMed:12935900}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 69 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
69
[view]
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Protein-Protein |
69
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8TDR0
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PhosphoSite |
PhosphoSite-Q8TDR0
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
26146
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UniGene |
Hs.631898
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RefSeq |
NP_001132962
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HUGO |
HGNC:17861
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OMIM |
607380
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CCDS |
CCDS46557
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HPRD |
09571
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IMGT |
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EMBL |
AC012485
AF230877
AF242456
AL080153
BC059174
CH471063
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GenPept |
AAF76984
AAH59174
AAL90444
AAX88977
CAB45744
EAW71157
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