Version 5.4
Homo sapiens Protein: KLHDC5
Summary
InnateDB Protein IDBP-24834.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KLHDC5
Protein Name kelch domain containing 5
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000370671
InnateDB Gene IDBG-24830 (KLHDC5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
Biological Process
GO:0000209 protein polyubiquitination
GO:0007067 mitotic nuclear division
GO:0032886 regulation of microtubule-based process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005819 spindle
GO:0031463 Cul3-RING ubiquitin ligase complex
Protein Structure and Domains
PDB ID
InterPro IPR000210 BTB/POZ-like
IPR006652 Kelch repeat type 1
IPR011333 BTB/POZ fold
IPR011705 BTB/Kelch-associated
PFAM PF01344
PF07707
PRINTS
PIRSF
SMART SM00225
SM00612
SM00875
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9P2K6
PhosphoSite PhosphoSite-Q9P2K6
TrEMBL B2RNT7
UniProt Splice Variant
Entrez Gene 57542
UniGene Hs.701439
RefSeq NP_065833
HUGO HGNC:29252
OMIM
CCDS CCDS31763
HPRD 17237
IMGT
EMBL AB037761 AC009511 AK095405 BC028742 BC108669 BC137116 BC137117 CH471094
GenPept AAH28742 AAI08670 AAI37117 AAI37118 BAA92578 BAG53048 EAW96571

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca