Version 5.4
Homo sapiens Protein: INO80C
Summary
InnateDB Protein IDBP-2489.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol INO80C
Protein Name INO80 complex subunit C
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000334473
InnateDB Gene IDBG-2485 (INO80C)
Protein Structure
UniProt Annotation
Function Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
Subcellular Localization Nucleus {ECO:0000269PubMed:18922472}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
Experimentally validated
Total 22 [view]
Protein-Protein 22 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0008150 biological_process
Cellular Component
GO:0005730 nucleolus
GO:0031011 Ino80 complex
GO:0071339 MLL1 complex
Protein Structure and Domains
PDB ID
InterPro IPR013272 YL1 nuclear, C-terminal
PFAM PF08265
PRINTS
PIRSF
SMART SM00993
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6PI98
PhosphoSite PhosphoSite-Q6PI98
TrEMBL K7EKI6
UniProt Splice Variant
Entrez Gene 125476
UniGene Hs.736893
RefSeq NP_919257
HUGO HGNC:26994
OMIM
CCDS CCDS11914
HPRD 10719
IMGT
EMBL AC007998 AK095502 AK300660 BC039404 CH471088
GenPept AAH39404 BAC04560 BAG62346 EAX01357

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca