InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Birc3

Summary

InnateDB Protein

IDBP-249118.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Birc3

Protein Name

baculoviral IAP repeat-containing 3

Synonyms

Api1; Api2; AW107670; Birc2; cIAP-1; cIAP-2; cIAP1; cIAP2; HIAP2; IAP1; IAP2; MIAP1; MIAP2; MIHB; MIHC; RNF49;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000111337

InnateDB Gene

IDBG-133177 (Birc3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 38 experimentally validated interaction(s) in this database.
They are also associated with 83 interaction(s) predicted by orthology.

Experimentally validated
Total	38 [view]
Protein-Protein	37 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	83 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity

Biological Process

GO:0007283	spermatogenesis
GO:0016567	protein ubiquitination
GO:0031398	positive regulation of protein ubiquitination
GO:0042981	regulation of apoptotic process
GO:0045087	innate immune response (InnateDB)
GO:0051291	protein heterooligomerization
GO:0060544	regulation of necroptotic process

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0043234	protein complex
GO:0045121	membrane raft

Protein Structure and Domains

PDB ID

MGI:1197007

InterPro

IPR001370 Baculoviral inhibition of apoptosis protein repeat

PFAM

PF00653

PRINTS

PIRSF

SMART

SM00238

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E0CZ20

UniProt Splice Variant

Entrez Gene

11796

UniGene

RefSeq

MGI ID

MGI Symbol

Birc3

OMIM

CCDS

HPRD

IMGT

EMBL

CT030639

GenPept