InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Hadhb

Summary

InnateDB Protein

IDBP-250988.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Hadhb

Protein Name

hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000110431

InnateDB Gene

IDBG-145305 (Hadhb)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Mitochondrion {ECO:0000250}. Mitochondrion inner membrane {ECO:0000250}. Mitochondrion outer membrane {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 37 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	37 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000062	fatty-acyl-CoA binding
GO:0003824	catalytic activity
GO:0003988	acetyl-CoA C-acyltransferase activity
GO:0004300	enoyl-CoA hydratase activity
GO:0016508	long-chain-enoyl-CoA hydratase activity
GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity
GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
GO:0032403	protein complex binding
GO:0051287	NAD binding

Biological Process

GO:0006635	fatty acid beta-oxidation
GO:0008152	metabolic process

Cellular Component

GO:0005739	mitochondrion
GO:0005741	mitochondrial outer membrane
GO:0005743	mitochondrial inner membrane
GO:0005783	endoplasmic reticulum
GO:0016507	mitochondrial fatty acid beta-oxidation multienzyme complex
GO:0042645	mitochondrial nucleoid