InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Acbd5

Summary

InnateDB Protein

IDBP-251551.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Acbd5

Protein Name

acyl-Coenzyme A binding domain containing 5

Synonyms

1300014E15Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000110172

InnateDB Gene

IDBG-141583 (Acbd5)

Protein Structure

UniProt Annotation

Function

Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters (By similarity). {ECO:0000250}.

Subcellular Localization

Peroxisome membrane {ECO:0000269PubMed:17768142}; Single-pass membrane protein {ECO:0000269PubMed:17768142}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000062	fatty-acyl-CoA binding
GO:0003674	molecular_function
GO:0008289	lipid binding

Biological Process

GO:0006810	transport
GO:0008150	biological_process
GO:0030242	peroxisome degradation

Cellular Component

GO:0005634	nucleus
GO:0005777	peroxisome
GO:0005778	peroxisomal membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0043231	intracellular membrane-bounded organelle