InnateDB Protein
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IDBP-252807.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Brd3
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Protein Name
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bromodomain containing 3
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Synonyms
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2410084F24Rik; AW060456; Fsrg2; ORFX; RINGL3;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000109574
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InnateDB Gene
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IDBG-151260 (Brd3)
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Protein Structure
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Function |
Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling and interaction with transcription factors. Regulates transcription of the CCND1 gene (By similarity). Regulates transcription by promoting the binding of the transcription factor GATA1 to its targets. {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000269PubMed:21536911}. Note=Detected on chromatin.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated |
Total |
7
[view]
|
Protein-Protein |
7
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
7 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1914632
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InterPro |
IPR001487
Bromodomain
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PFAM |
PF00439
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PRINTS |
PR00503
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PIRSF |
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SMART |
SM00297
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TIGRFAMs |
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Modification |
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SwissProt |
Q8K2F0
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PhosphoSite |
PhosphoSite-Q8K2F0
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TrEMBL |
Q5CCJ9
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UniProt Splice Variant |
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Entrez Gene |
67382
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UniGene |
Mm.415648
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RefSeq |
NP_001107046
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MGI ID |
2L5E
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MGI Symbol |
Brd3
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OMIM |
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CCDS |
CCDS50546
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HPRD |
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IMGT |
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EMBL |
AB206708
AF269193
AK037435
AK076472
AL772282
BC031536
CH466542
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GenPept |
AAF78072
AAH31536
BAC29806
BAC36359
BAD91008
EDL08365
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