Version 5.4
Mus musculus Protein: B3galt5
Summary
InnateDB Protein IDBP-253121.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol B3galt5
Protein Name UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
Synonyms 1190002B21Rik; AU045265; b3Galt-V;
Species Mus musculus
Ensembl Protein ENSMUSP00000109431
InnateDB Gene IDBG-179961 (B3galt5)
Protein Structure
UniProt Annotation
Function Catalyzes the transfer of Gal to GlcNAc-based acceptors with a preference for the core3 O-linked glycan GlcNAc(beta1,3)GalNAc structure. Can use glycolipid LC3Cer as an efficient acceptor. Also catalyzes the transfer of Gal to the terminal GalNAc unit of the globoside GB4, thereby synthesizing the glycolipid GB5, also known as the stage-specific embryonic antigen-3 (SSEA-3).
Subcellular Localization Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in brain and kidney.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008378 galactosyltransferase activity
Biological Process
GO:0006486 protein glycosylation
Cellular Component
GO:0000139 Golgi membrane
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2136878
InterPro IPR002659 Glycosyl transferase, family 31
IPR029044 Nucleotide-diphospho-sugar transferases
PFAM PF01762
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9JI67
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 93961
UniGene Mm.401166
RefSeq NP_001116465
MGI ID
MGI Symbol B3galt5
OMIM
CCDS CCDS28356
HPRD
IMGT
EMBL AF254738 BC057887
GenPept AAF86241 AAH57887

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca