InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Swi5

Summary

InnateDB Protein

IDBP-253968.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Swi5

Protein Name

SWI5 recombination repair homolog (yeast)

Synonyms

1500019F05Rik; 2900010J23Rik; AI046671;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000109022

InnateDB Gene

IDBG-159259 (Swi5)

Protein Structure

UniProt Annotation

Function

Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination. {ECO:0000269PubMed:20976249}.

Subcellular Localization

Nucleus {ECO:0000269PubMed:20976249}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0000724	double-strand break repair via homologous recombination
GO:0071479	cellular response to ionizing radiation

Cellular Component

GO:0005634	nucleus
GO:0032798	Swi5-Sfr1 complex

Protein Structure and Domains

PDB ID

MGI:1920181

InterPro

IPR010760 DNA repair protein, Swi5

PFAM

PF07061

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8K3D3

PhosphoSite

PhosphoSite-

TrEMBL

E3WH32

UniProt Splice Variant

Entrez Gene

72931

UniGene

Mm.27344

RefSeq

MGI ID

MGI Symbol

Swi5

OMIM

CCDS

CCDS50566

HPRD

IMGT

EMBL

AB597964 AB597965 AK013517 AK166608 AL808027 BC021748 CH466542

GenPept

AAH21748 BAC25409 BAE38890 BAJ25750 BAJ25751 CAM15841 CAM15843 EDL08533 EDL08534