InnateDB Protein
|
IDBP-256631.5
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Last Modified
|
2012-02-14 [Report errors or provide feedback]
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Gene Symbol
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Foxm1
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Protein Name
|
forkhead box M1
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Synonyms
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AA408308; AW554517; BB238854; Fkh16; Foxm1b; HFH-11B; MPHOSPH2; Mpm2; WIN;
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Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000107776
|
InnateDB Gene
|
IDBG-191010 (Foxm1)
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Protein Structure
|
|
Function |
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
|
This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 35 interaction(s) predicted by orthology.
Experimentally validated |
Total |
3
[view]
|
Protein-Protein |
2
[view]
|
Protein-DNA |
1
[view]
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
35 [view]
|
|
|
Molecular Function |
Accession |
GO Term |
GO:0003690
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double-stranded DNA binding
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GO:0003700
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sequence-specific DNA binding transcription factor activity
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GO:0003705
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RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
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GO:0008134
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transcription factor binding
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GO:0008301
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DNA binding, bending
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GO:0043565
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sequence-specific DNA binding
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GO:0044212
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transcription regulatory region DNA binding
|
|
Biological Process |
GO:0000122
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negative regulation of transcription from RNA polymerase II promoter
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GO:0001570
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vasculogenesis
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GO:0001889
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liver development
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GO:0006355
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regulation of transcription, DNA-templated
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GO:0006366
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transcription from RNA polymerase II promoter
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GO:0007389
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pattern specification process
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GO:0008284
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positive regulation of cell proliferation
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GO:0009888
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tissue development
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GO:0032873
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negative regulation of stress-activated MAPK cascade
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GO:0042127
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regulation of cell proliferation
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GO:0045944
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positive regulation of transcription from RNA polymerase II promoter
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GO:0046578
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regulation of Ras protein signal transduction
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GO:0051090
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regulation of sequence-specific DNA binding transcription factor activity
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GO:0071156
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regulation of cell cycle arrest
|
|
Cellular Component |
|
PDB ID |
MGI:1347487
|
InterPro |
IPR001766
Transcription factor, fork head
|
PFAM |
PF00250
|
PRINTS |
PR00053
|
PIRSF |
|
SMART |
SM00339
|
TIGRFAMs |
|
Modification |
|
SwissProt |
|
PhosphoSite |
PhosphoSite-
|
TrEMBL |
E9Q7Y0
|
UniProt Splice Variant |
|
Entrez Gene |
14235
|
UniGene |
Mm.42148
|
RefSeq |
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MGI ID |
|
MGI Symbol |
Foxm1
|
OMIM |
|
CCDS |
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HPRD |
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IMGT |
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EMBL |
AC116573
|
GenPept |
|
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