Version 5.4
Homo sapiens Protein: CCNI
Summary
InnateDB Protein IDBP-25683.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CCNI
Protein Name cyclin I
Synonyms CCNI1; CYC1; CYI;
Species Homo sapiens
Ensembl Protein ENSP00000237654
InnateDB Gene IDBG-25681 (CCNI)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity Highest levels in adult heart, brain and skeletal muscle. Lower levels in adult placenta, lung, kidney and pancreas. Also high levels in fetal brain and lower levels in fetal lung, liver and kidney. Also abundant in testis and thyroid. {ECO:0000269PubMed:7493655}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007283 spermatogenesis
GO:0051726 regulation of cell cycle
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR006671 Cyclin, N-terminal
IPR013763 Cyclin-like
PFAM PF00134
PRINTS
PIRSF
SMART SM00385
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q14094
PhosphoSite PhosphoSite-Q14094
TrEMBL D6RH01
UniProt Splice Variant
Entrez Gene 10983
UniGene Hs.731437
RefSeq NP_006826
HUGO HGNC:1595
OMIM
CCDS CCDS3580
HPRD 16690
IMGT
EMBL AC104771 AC111196 AF135162 AK312632 AY207372 BC000420 BC004975 BT020019 CH471057 D50310
GenPept AAF43786 AAH00420 AAH04975 AAO13492 AAV38822 BAA08849 BAG35517 EAX05808 EAX05809 EAX05810

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca