InnateDB Protein
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IDBP-257712.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Timm10
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Protein Name
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translocase of inner mitochondrial membrane 10 homolog (yeast)
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Synonyms
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Tim13; Timm13a;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000107258
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InnateDB Gene
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IDBG-185410 (Timm10)
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Protein Structure
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Function |
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity). {ECO:0000250}.
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Subcellular Localization |
Mitochondrion inner membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Intermembrane side {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
14 [view]
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Molecular Function |
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Biological Process |
GO:0045039
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protein import into mitochondrial inner membrane
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GO:0072321
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chaperone-mediated protein transport
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Cellular Component |
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PDB ID |
MGI:1353429
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InterPro |
IPR004217
Tim10/DDP family zinc finger
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PFAM |
PF02953
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P62073
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PhosphoSite |
PhosphoSite-P62073
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
30059
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UniGene |
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RefSeq |
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MGI ID |
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MGI Symbol |
Timm10
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OMIM |
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CCDS |
CCDS38161
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HPRD |
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IMGT |
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EMBL |
AF150090
AK008088
BC031448
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GenPept |
AAD39996
AAH31448
BAB25452
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