InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cat

Summary

InnateDB Protein

IDBP-258696.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Cat

Protein Name

catalase

Synonyms

2210418N07; Cas-1; Cas1; Cs-1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000106798

InnateDB Gene

IDBG-193911 (Cat)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004046	aminoacylase activity
GO:0004096	catalase activity
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor
GO:0020037	heme binding

Biological Process

GO:0006641	triglyceride metabolic process
GO:0006979	response to oxidative stress
GO:0008203	cholesterol metabolic process
GO:0009060	aerobic respiration
GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
GO:0020027	hemoglobin metabolic process
GO:0032088	negative regulation of NF-kappaB transcription factor activity
GO:0042744	hydrogen peroxide catabolic process
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005739	mitochondrion
GO:0005777	peroxisome
GO:0005778	peroxisomal membrane

Protein Structure and Domains

PDB ID

MGI:88271

InterPro

IPR010582 Catalase immune-responsive domain
IPR011614 Catalase core domain
IPR020835 Catalase-like domain

PFAM

PF06628
PF00199

PRINTS

PIRSF

SMART

SM01060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A2AL20

UniProt Splice Variant

Entrez Gene

12359

UniGene

Mm.490469

RefSeq

MGI ID

MGI Symbol

Cat

OMIM

CCDS

HPRD

IMGT

EMBL

AL773505 CH466519

GenPept

EDL27696