Version 5.4
Mus musculus Protein: Capn3
Summary
InnateDB Protein IDBP-259658.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Capn3
Protein Name calpain 3
Synonyms AI323605; Capa-3; Capa3; Lp82; p94;
Species Mus musculus
Ensembl Protein ENSMUSP00000106347
InnateDB Gene IDBG-259652 (Capn3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004198 calcium-dependent cysteine-type endopeptidase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0006508 proteolysis
GO:0030239 myofibril assembly
GO:0045214 sarcomere organization
Cellular Component
GO:0005622 intracellular
Protein Structure and Domains
PDB ID MGI:107437
InterPro IPR001300 Peptidase C2, calpain, catalytic domain
IPR002048 EF-hand domain
IPR022682 Peptidase C2, calpain, large subunit, domain III
IPR022683 Peptidase C2, calpain, domain III
IPR022684 Peptidase C2, calpain family
PFAM PF00648
PF00036
PF13202
PF13405
PF01067
PRINTS PR00704
PIRSF
SMART SM00230
SM00054
SM00720
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q920R8
UniProt Splice Variant
Entrez Gene 12335
UniGene Mm.458021
RefSeq
MGI ID
MGI Symbol Capn3
OMIM
CCDS
HPRD
IMGT
EMBL AB050200 AK079673 AL935121
GenPept BAB70478 BAC37720

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca