InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tfpt

Summary

InnateDB Protein

IDBP-264104.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tfpt

Protein Name

TCF3 (E2A) fusion partner

Synonyms

2400004F01Rik; AI450389; Amida; FB1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000104281

InnateDB Gene

IDBG-135731 (Tfpt)

Protein Structure

UniProt Annotation

Function

Appears to promote apoptosis in a p53/TP53-independent manner. {ECO:0000250}.Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	25 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0019901	protein kinase binding
GO:0046982	protein heterodimerization activity

Biological Process

GO:0006281	DNA repair
GO:0006310	DNA recombination
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006915	apoptotic process
GO:0043065	positive regulation of apoptotic process
GO:0097190	apoptotic signaling pathway