InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Hsd17b14

Summary

InnateDB Protein

IDBP-266004.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Hsd17b14

Protein Name

hydroxysteroid (17-beta) dehydrogenase 14

Synonyms

0610039E24Rik; Dhrs10; retSDR3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000103381

InnateDB Gene

IDBG-183702 (Hsd17b14)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity
GO:0004303	estradiol 17-beta-dehydrogenase activity
GO:0005515	protein binding
GO:0016491	oxidoreductase activity
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity
GO:0050662	coenzyme binding

Biological Process

GO:0006694	steroid biosynthetic process
GO:0006706	steroid catabolic process
GO:0008152	metabolic process
GO:0044237	cellular metabolic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005813	centrosome
GO:0005829	cytosol

Protein Structure and Domains

PDB ID

MGI:1913315

InterPro

IPR001509 NAD-dependent epimerase/dehydratase
IPR002198 Short-chain dehydrogenase/reductase SDR
IPR002225 3-beta hydroxysteroid dehydrogenase/isomerase
IPR002347 Glucose/ribitol dehydrogenase
IPR002424 Alcohol dehydrogenase, insect-type
IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
IPR013968 Polyketide synthase, KR

PFAM

PF01370
PF00106
PF01073
PF08659

PRINTS

PR00080
PR00081
PR01167
PR01397

PIRSF

PIRSF000126

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt