InnateDB Protein
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IDBP-266488.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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1110054O05Rik
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Protein Name
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RIKEN cDNA 1110054O05 gene
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Synonyms
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1110054O05Rik; 2610312O17Rik; AA399876; Ssbip1;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000103150
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InnateDB Gene
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IDBG-151697 (1110054O05Rik)
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Protein Structure
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Function |
Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single- stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination- dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000250}. Note=Localizes to nuclear foci following DNA damage. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated |
Total |
2
[view]
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Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
6 [view]
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PDB ID |
MGI:1913459
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
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PhosphoSite |
PhosphoSite-
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TrEMBL |
Z4YLT1
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UniProt Splice Variant |
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Entrez Gene |
66209
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UniGene |
Mm.51988
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RefSeq |
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MGI ID |
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MGI Symbol |
Inip
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AL806512
AL929501
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GenPept |
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