InnateDB Protein
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IDBP-26692.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ALG10
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Protein Name
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asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog (S. pombe)
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000266483
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InnateDB Gene
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IDBG-26690 (ALG10)
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Protein Structure
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Function |
Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol.
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Subcellular Localization |
Endoplasmic reticulum membrane; Multi-pass membrane protein.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0016758
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transferase activity, transferring hexosyl groups
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Biological Process |
GO:0006488
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dolichol-linked oligosaccharide biosynthetic process
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GO:0018279
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protein N-linked glycosylation via asparagine
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GO:0043687
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post-translational protein modification
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GO:0044267
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cellular protein metabolic process
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Cellular Component |
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PDB ID |
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InterPro |
IPR016900
Glucosyltransferase Alg10
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PFAM |
PF04922
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PRINTS |
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PIRSF |
PIRSF028810
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q5BKT4
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PhosphoSite |
PhosphoSite-Q5BKT4
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
84920
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UniGene |
Hs.609863
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RefSeq |
NP_116223
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HUGO |
HGNC:23162
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OMIM |
603313
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CCDS |
CCDS41769
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HPRD |
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IMGT |
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EMBL |
AJ312278
AK027657
BC070347
BC090948
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GenPept |
AAH70347
AAH90948
BAB55272
CAC41349
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