InnateDB Protein
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IDBP-268220.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Scp2
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Protein Name
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sterol carrier protein 2, liver
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Synonyms
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AA409774; AA409893; C76618; C79031; ns-LTP; NSL-TP; SCP-2; SCP-X; SCPX;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000102312
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InnateDB Gene
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IDBG-172393 (Scp2)
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Protein Structure
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Function |
Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis.
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Subcellular Localization |
Cytoplasm. Note=Cytoplasmic in the liver and also associated with mitochondria especially in steroidogenic tissues.Isoform SCP2: Mitochondrion.Isoform SCPx: Peroxisome. Note=Interaction with PEX5 is essential for peroxisomal import. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Present at low levels in all tissues examined but expressed predominantly in the liver.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.
Experimentally validated |
Total |
14
[view]
|
Protein-Protein |
13
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
27 [view]
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|
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:98254
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InterPro |
IPR003033
SCP2 sterol-binding domain
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PFAM |
PF02036
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P32020
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PhosphoSite |
PhosphoSite-P32020
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
20280
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UniGene |
Mm.487288
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RefSeq |
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MGI ID |
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MGI Symbol |
Scp2
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AK002425
AK004860
AL844206
BC018384
BC034613
M62361
M91458
X91150
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GenPept |
AAA40098
AAA40099
AAH18384
AAH34613
BAB22092
CAA62592
CAM27075
CAM27076
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