InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Snrnp40

Summary

InnateDB Protein

IDBP-269698.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Snrnp40

Protein Name

small nuclear ribonucleoprotein 40 (U5)

Synonyms

0610009C03Rik; Prp8bp; Wdr57;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000101616

InnateDB Gene

IDBG-217080 (Snrnp40)

Protein Structure

UniProt Annotation

Function

Component of the U5 small nuclear ribonucleoprotein (snRNP) complex. The U5 snRNP is part of the spliceosome, a multiprotein complex that catalyzes the removal of introns from pre-messenger RNAs (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	28 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006397	mRNA processing
GO:0008380	RNA splicing

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0071013	catalytic step 2 spliceosome

Protein Structure and Domains

PDB ID

MGI:1913835

InterPro

IPR001680 WD40 repeat
IPR017986 WD40-repeat-containing domain
IPR020472 G-protein beta WD-40 repeat

PFAM

PF00400

PRINTS

PR00320

PIRSF

SMART

SM00320

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q6PE01

PhosphoSite

PhosphoSite-Q6PE01

TrEMBL

UniProt Splice Variant

Entrez Gene

66585

UniGene

Mm.423019

RefSeq

NP_079921

MGI ID

MGI Symbol

Snrnp40

OMIM

CCDS

CCDS38892

HPRD

IMGT

EMBL

AK002371 AK169605 BC058365

GenPept

AAH58365 BAB22049 BAE41255