Version 5.4
Mus musculus Protein: Cstf1
Summary
InnateDB Protein IDBP-274280.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cstf1
Protein Name cleavage stimulation factor, 3' pre-RNA, subunit 1
Synonyms 1700057K18Rik; AI788832;
Species Mus musculus
Ensembl Protein ENSMUSP00000112076
InnateDB Gene IDBG-213287 (Cstf1)
Protein Structure
UniProt Annotation
Function One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006397 mRNA processing
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1914587
InterPro IPR001680 WD40 repeat
IPR017986 WD40-repeat-containing domain
PFAM PF00400
PRINTS
PIRSF
SMART SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99LC2
PhosphoSite PhosphoSite-Q99LC2
TrEMBL A2APA3
UniProt Splice Variant
Entrez Gene 67337
UniGene Mm.447539
RefSeq NP_077161
MGI ID
MGI Symbol Cstf1
OMIM
CCDS CCDS17130
HPRD
IMGT
EMBL AK011943 AK050686 AK078667 AK145001 AL833787 BC003440
GenPept AAH03440 BAB27929 BAC34379 BAC37353 BAE26180

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca