Version 5.4
Homo sapiens Protein: NMB
Summary
InnateDB Protein IDBP-27677.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NMB
Protein Name neuromedin B
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000353664
InnateDB Gene IDBG-27675 (NMB)
Protein Structure
UniProt Annotation
Function Stimulates smooth muscle contraction in a manner similar to that of bombesin.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
Biological Process
GO:0007165 signal transduction
GO:0007218 neuropeptide signaling pathway
GO:0007267 cell-cell signaling
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR000874 Bombesin/neuromedin-B/ranatensin peptide family
PFAM PF02044
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P08949
PhosphoSite PhosphoSite-P08949
TrEMBL
UniProt Splice Variant
Entrez Gene 4828
UniGene Hs.386470
RefSeq NP_066563
HUGO HGNC:7842
OMIM 162340
CCDS CCDS10332
HPRD 01210
IMGT
EMBL AC048382 BC007407 BC007431 BC008603 M21551
GenPept AAA59934 AAH07407 AAH07431 AAH08603

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca