Version 5.4
Homo sapiens Protein: TMEM107
Summary
InnateDB Protein IDBP-28123.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMEM107
Protein Name transmembrane protein 107
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000314116
InnateDB Gene IDBG-28121 (TMEM107)
Protein Structure
UniProt Annotation
Function Plays a role in cilia formation and embryonic patterning. Requires for normal Sonic hedgehog (Shh) signaling in the neural tube and acts in combination with GLI2 and GLI3 to pattern ventral and intermediate neuronal cell types (By similarity). {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
GO:0021532 neural tube patterning
GO:0042384 cilium assembly
GO:0042733 embryonic digit morphogenesis
Cellular Component
GO:0005575 cellular_component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6UX40
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 84314
UniGene
RefSeq NP_115730
HUGO HGNC:28128
OMIM
CCDS CCDS11132
HPRD 14400
IMGT
EMBL AC129492 AF311338 AK127891 AY358525 BC070231 BC127649
GenPept AAH70231 AAI27650 AAK38512 AAQ88889 BAC87177

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca